The ISV research group offers a broad spectrum of expertise in both methodologies and thematic areas of primary care. The group is fully integrated in the RICAPPS network (Network for Research in Chronicity, Primary Care and Health Promotion, RICORS program) as Dr. Ramos is also the coordinator of the network. The ISV group is multidisciplinary: it includes primary care physicians, epidemiologists, nurses, biologists, mathematicians, and biostatisticians with and biostatisticians (who ensure accurate and rigorous data analysis). Its research focuses on three main lines of investigation, which we intend to continue in the next three years. These lines are: 1) evaluation of preventive interventions and study of the efficacy of drugs used in primary prevention, using real-world data. 2) Epidemiology of cardiovascular diseases, especially asymptomatic ones. 3) The design of decision support tools with mathematical models.